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CV Henrik Källberg
Date of birth
1973-05-31
Family
Sambo, two children, 3 and 5 years old
Education
Gymnasium
4-years of technical college (Swedish Judo association college) graduation 1993
Stage III instructor Judo
University
Högskolan i Örebro
Matemathics, economy etc.
Psychology 45 p
Bsc. Biomedicine
Physiology 125 p
University of Stockholm
Statistics 65 p
Research education
PhD student in epidemiology, Institutet för Miljömedicin, Karolinska Institutet, June 2003 – January 2009. Main supervisor: professor Lars Alfredsson, KI, Co supervisor professor Lars Klareskog, KI.
Doktorsexamen
Dissertation in Epidemiology, Karolinska Institutet, Thesis entitled ”Role of Genes and Environment for the development of Rheumatoid Arthritis” the 30 of Januari 2009.
Doctroral Certificate recived the 12 of March 2009
Doctoral courses
2003 How to Write and Publish a Scientific Paper (1,5 poäng).
Causal Inference from Longitudinal Data (1,5 poäng).
2004 Basic Course in Clinical Epidemiology (1,5 poäng).
Applied Longitudinal Analysis of Continuous Data (1,5 poäng).
2005 Biostatistics II (1,5 poäng)
Epidemiology II (1,5 poäng)
2006 Biostatistics III (1,5 poäng)
How to present research findings (1,5 poäng)
Genetic epidemiology (3 poäng)
Epidemiology III (1,5 poäng)
Bayesian inference, Post graduate course in statistics, SU (7,5 poäng)
2008 Systems biology and the Omics cascade (1,5 poäng)
Employments/other assignments
2010- Research fellow Harvard Medical School, Boston, US
2010- Visiting Post Doc Broad Institute, Cambridge, US
2008- paid reviewer for the journal Acta Pedeatrica
2005, 2007 Paternal leave totally 12 months
2001-2002 TA. statistics (A- and B-level) statistiska instutionen, SU
2006- Teacher quantative research methods and research methodology Naprapathögskolan
2003-2006 Teacher biostatistics, master of public health program , KI
2008 Teacher SAS programming for researchers, KI
2004 - 2006 Tutor for two MPH students, KI
1999-2002 Sonographer, physiology assistant, S:t Görans sjukhus
2000- Emergency police training, Försvarsenheten, RPS
1998 Research secretary, Institution of excercise and health, Högskolan i Örebro
1997-1998 nurse assistant, Lung clinic, Regionsjukhuset Örebro
1993-1994 Sergent Recon platoon, Sniper, I2/FO 52
Publications
Familial risks and heritability of rheumatoid arthritis: role of rheumatoid factor/anti-citrullinated protein antibody status, number and type of affected relatives, sex, and age.
Frisell T, Holmqvist M, Källberg H, Klareskog L, Alfredsson L, Askling J.
Arthritis Rheum. 2013 Nov;65(11):2773-82
Parity and the risk of developing rheumatoid arthritis: results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis study.
Orellana C, Wedrén S, Källberg H, Holmqvist M, Karlson EW, Alfredsson L, Bengtsson C; EIRA Study Group.
Ann Rheum Dis. 2013
Thyroxin substitution and the risk of developing rheumatoid arthritis; results from the Swedish population-based EIRA study.
Bengtsson C, Padyukov L, Källberg H, Saevarsdottir S.
Ann Rheum Dis. 2013 Apr 23. [Epub ahead of print]
Long-term growth of children with autoantibody-mediated congenital heart block.
Skog A, Eliasson H, Tingström J, Källberg H, Salomonsson S; Swedish Congenital Heart Block Study Group, Sonesson SE, Wahren-Herlenius M.
Acta Paediatr. 2013 Jul;102(7):718-26
HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus.
Lundström E, Gustafsson JT, Jönsen A, Leonard D, Zickert A, Elvin K, Sturfelt G, Nordmark G, Bengtsson AA, Sundin U, Källberg H, Sandling JK, Syvänen AC, Klareskog L, Gunnarsson I, Rönnblom L, Padyukov L, Svenungsson E.
Ann Rheum Dis. 2013 Jun;72(6):1018-25.
Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study.
Hart JE, Källberg H, Laden F, Bellander T, Costenbader KH, Holmqvist M, Klareskog L, Alfredsson L, Karlson EW.
Ann Rheum Dis. 2013 Jun;72(6):888-94.
Lundberg K, Bengtsson C, Kharlamova N, Reed E, Jiang X, Kallberg H, Pollak-Dorocic I, Israelsson L, Kessel C, Padyukov L, Holmdahl R, Alfredsson L, Klareskog L.
Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile.
Ann Rheum Dis. 2013 May;72(5):652-8
Ding B, Källberg H, Klareskog L, Padyukov L, Alfredsson L.
Eur J Epidemiol. 2011 Apr 26. [Epub ahead of print]
GEIRA: gene-environment and gene-gene interaction research application.
Ambrosi A, Salomonsson S, Eliasson H, Zeffer E, Skog A, Dzikaite V, Bergman G, Fernlund E, Tingström J, Theander E, Rydberg A, Skogh T, Öhman A, Lundström U, Mellander M, Winqvist O, Fored M, Ekbom A, Alfredsson L, Källberg H, Olsson T, Gadler F, Jonzon A, Kockum I, Sonesson SE, Wahren-Herlenius M.
Ann Rheum Dis. 2012 Mar;71(3):334-40
Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern.
Eli A Stahl, Daniel Wegmann, Gosia Trynka, Javier Gutierrez-Achury, Ron Do, Benjamin F Voight, Peter Kraft, Robert Chen, Henrik J Kallberg, Fina A S Kurreeman, Diabetes Genetics Replication and Meta-analysis Consortium, Myocardial Infarction Genetics Consortium, Sekar Kathiresan, Cisca Wijmenga, Peter K Gregersen, Lars Alfredsson, Katherine A Siminovitch, Jane Worthington, Paul I W de Bakker, Soumya Raychaudhuri, Robert M Plenge.
Nat Genet. 2012 Mar 25. [Epub ahead of print]
Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis.
Lundström SL, Yang J, Källberg HJ, Thunberg S, Gafvelin G, Haeggström JZ, Grönneberg R, Grunewald J, van Hage M, Hammock BD, Eklund A, Wheelock AM, Wheelock CE.
PLoS One. 2012;7(3)
Allergic Asthmatics Show Divergent Lipid Mediator Profiles from Healthy Controls Both at Baseline and following Birch Pollen Provocation.
Sverdrup BM, Källberg H, Klareskog L, Alfredsson L; Epidemiological Investigation of Rheumatoid Arthritis Study Group.
Arthritis Res Ther. 2012 Feb 28;14(1):R41
Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study.
Lundberg K, Bengtsson C, Kharlamova N, Reed E, Jiang X, Kallberg H, Pollak-Dorocic I, Israelsson L, Kessel C, Padyukov L, Holmdahl R, Alfredsson L, Klareskog L.
Ann Rheum Dis. 2012 Sep 8. [Epub ahead of print]
Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile.
Hart JE, Källberg H, Laden F, Bellander T, Costenbader KH, Holmqvist M, Klareskog L, Alfredsson L, Karlson EW.
Ann Rheum Dis. 2012 Jul 24. [Epub ahead of print]
Ambient air pollution exposures and risk of rheumatoid arthritis: results from the Swedish EIRA case-control study.
Lundström E, Gustafsson JT, Jönsen A, Leonard D, Zickert A, Elvin K, Sturfelt G, Nordmark G, Bengtsson AA, Sundin U, Källberg H, Sandling JK, Syvänen AC, Klareskog L, Gunnarsson I, Rönnblom L, Padyukov L, Svenungsson E.
Ann Rheum Dis. 2012 Aug 14. [Epub ahead of print]
HLA-DRB1*04/*13 alleles are associated with vascular disease and antiphospholipid antibodies in systemic lupus erythematosus.
Hart JE, Källberg H, Laden F, Costenbader KH, Yanosky JD, Klareskog L, Alfredsson L, Karlson EW. Arthritis Care Res (Hoboken). 2013 Feb 11.[Epub ahead of print] Ambient air pollution exposures and risk of rheumatoid arthritis in the Nurses' Health Study.
Amanda Skog, Håkan Eliasson, Joanna Tingström, Henrik Källberg, Stina Salomonsson, The Swedish Congenital Heart Block Study Group, Sven-Erik Sonesson, Marie Wahren-Herlenius. Acta Paediatrica [In press] Long-term growth of children with autoantibody-mediated congenital heart block.
Henrik Källberg, Veronica Vieira, Marie Holmqvist, Jaime E Hart, Karen H Costenbader , Camilla Bengtsson ,Lars Klareskog, Elizabeth W Karlson, Lars Alfredsson. Scandinavian Journal of Rheumatology [In press] Regional differences regarding risk of developing Rheumatoid Arthritis in Stockholm County, Sweden. -Results from the Swedish Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study
Källberg H, Ding B, Padyukov L, Bengtsson C, Rönnelid J, Klareskog L, Alfredsson L; EIRA Study Group.
Ann Rheum Dis. 2010 Dec 13
Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke.
Bengtsson C, Kapetanovic MC, Källberg H, Sverdrup B, Nordmark B, Klareskog L, Alfredsson L; EIRA Study Group.
Ann Rheum Dis. 2010 Oct;69(10):1831-3.
Common vaccinations among adults do not increase the risk of developing rheumatoid arthritis: results from the Swedish EIRA study.
Keenan BT, Chibnik LB, Cui J, Ding B, Padyukov L, Kallberg H, Bengtsson C, Klareskog L, Alfredsson L, Karlson EW.
Arthritis Rheum. 2010 Nov;62(11):3196-210
Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis.
Källberg H, Alfredsson L, Feychting M, Ahlbom A.
Eur J Epidemiol. 2010 May;25(5):283-4.
Don't split your data.
Seddighzadeh M, Korotkova M, Källberg H, Ding B, Daha N, Kurreeman FA, Toes RE, Huizinga TW, Catrina AI, Alfredsson L, Klareskog L, Padyukov L.
Eur J Hum Genet. 2010 Jul;18(7):821-6.
Evidence for interaction between 5-hydroxytryptamine (serotonin) receptor 2A and MHC type II molecules in the development of rheumatoid arthritis.
Stolt P, Yahya A, Bengtsson C, Källberg H, Rönnelid J, Lundberg I, Klareskog L, Alfredsson L; EIRA Study Group.
Ann Rheum Dis. 2010 Jun;69(6):1072-6.
Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis.
Mahdi H, Fisher BA, Källberg H, Plant D, Malmström V, Rönnelid J, Charles P, Ding B, Alfredsson L, Padyukov L, Symmons DP, Venables PJ, Klareskog L, Lundberg K.
Nat Genet. 2009 Nov 8. [Epub ahead of print]
Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis.
Lundström E, Källberg H, Alfredsson L, Klareskog L, Padyukov L.
Arthritis Rheum. 2009 Jun;60(6):1597-603.
Gene-environment interaction between the DRB1 shared epitope and smoking in the risk of anti-citrullinated protein antibody-positive rheumatoid arthritis: all alleles are important.
Liao KP, Gunnarsson M, Källberg H, Ding B, Plenge RM, Padyukov L, Karlson EW, Klareskog L, Askling J, Alfredsson L.
Arthritis Rheum. 2009 Mar;60(3):653-60.
Specific association of type 1 diabetes mellitus with anti-cyclic citrullinated peptide-positive rheumatoid arthritis.
Lundström E, Källberg H, Smolnikova M, Ding B, Rönnelid J, Alfredsson L, Klareskog L, Padyukov L.
Arthritis Rheum. 2009 Mar 30;60(4):924-930.
Opposing effects of HLA-DRB1*13 alleles on the risk of developing anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.
Kallberg H.
J Rheumatol. 2008 Sep;35(9):1695-6.
Rheumatoid arthritis and lung cancer: you probably heard it before.
Marcus Ronninger, Henrik Källberg, Emeli Lundström, Annmarie Lindahl, Lars Klareskog, Lars Alfredsson, Leonid Padyukov.
Complexity of a complex disease; understanding genes, environment and immunity in rheumatoid arthritis development.Future Rheumatology, Oct 2007, Vol. 2, No. 5, Pages 485-492
Källberg H, Jacobsen S, Bengtsson C, Pedersen M, Padyukov L, Garred P, Frisch M, Karlson EW, Klareskog L, Alfredsson L.
Ann Rheum Dis. 2009 Feb;68(2):222-7. Epub 2008 Jun 5.
Alcohol consumption is associated with decreased risk of rheumatoid arthritis: results from two Scandinavian case-control studies.
Olsson LM, Lindqvist AK, Källberg H, Padyukov L, Burkhardt H, Alfredsson L, Klareskog L, Holmdahl R. Arthritis Res Ther. 2007;9(5):R98.
A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity.
Kallberg H, Padyukov L, Plenge RM, Ronnelid J, Gregersen PK, van der Helm-van Mil AH, Toes RE, Huizinga TW, Klareskog L, Alfredsson L; Epidemiological Investigation of Rheumatoid Arthritis study group. Am J Hum Genet. 2007 May;80(5):867-75. Epub 2007 Apr 2.
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.
Källberg H, Ahlbom A, Alfredsson L.
Eur J Epidemiol. 2006;21(8):571-3. Epub 2006 Sep 13. No abstract available.
Calculating measures of biological interaction using R.
Klareskog L, Stolt P, Lundberg K, Källberg H, Bengtsson C, Grunewald J, Rönnelid J, Harris HE, Ulfgren AK, Rantapää-Dahlqvist S, Eklund A, Padyukov L, Alfredsson L.
Arthritis Rheum. 2006 Jan;54(1):38-46.
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
Sverdrup B, Källberg H, Bengtsson C, Lundberg I, Padyukov L, Alfredsson L, Klareskog L; Epidemiological Investigation of Rheumatoid Arthritis Study Group.
Arthritis Res Ther. 2005;7(6):R1296-303. Epub 2005 Sep 23.
Association between occupational exposure to mineral oil and rheumatoid arthritis: results from the Swedish EIRA case-control study.
Andersson T, Alfredsson L, Källberg H, Zdravkovic S, Ahlbom A.
Eur J Epidemiol. 2005;20(7):575-9.
Calculating measures of biological interaction.
Stolt P, Källberg H, Lundberg I, Sjögren B, Klareskog L, Alfredsson L; EIRA study group.
Ann Rheum Dis. 2005 Apr;64(4):582-6. Epub 2004 Aug 19.
Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA study.
Research fundings
CFV (Centre for Caring Sciences, Karolinska Institutet), 6 months, 2004
FAS, 6 months 2009
COFAS 18 months 2010-2011
SFO, 56 kkr
Junior Faculty, 500 kkr * 2
KI fonder 25 kkr *2
Current employer:
Karolinska Institutet, Institutet för Miljömedicin
Nobels väg 13, Box 120, 171 77 Stockholm
Book Chapters:
Chapter 1 and 2 in the book entitled: Between the the line of the Genetic Code, Elsivier publishing
Scientific conferences and awards:
- AmericanCollege of Rheumatism(ACR), San Diego 2007, Poster presentation
- European League Against Rheumatism (EULAR), Amsterdam 2006, Poster presentation
- European League Against Rheumatism (EULAR), Barcelona 2007, Oral and poster presentation
- EULAR abstract award, European League Against Rheumatism (EULAR), Barcelona 2007
Extra
Brown Belt in Brazilian JiuJitsu
Black Belt in Judo
Telemark skier
Crossfit wannabe
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CV Henrik Källberg